{\N}-substitution of 4-phenylpiperidine4-ethyl-carboxylate derivatives results in nalgesics with varying activities. Match the substitutions with activities GROUP I Substitution at N GROUP II Analgesics (P) - {\CH}_3 (1) Fentanyl (Q) - {\CH}_2- {\CH}_2- ( {\C}_6 {\H}_4) - {\NH}_2 (2) Diphenoxylate (R) - {\CH}_2- {\CH}_2- {\C}- ( {\C}_6 {\H}_5) _2- {\CN} (3) Pethidine (S) - {\CH}_2- {\CH}_2- {\C}_6 {\H}_5 (4) Anileridine

Correct Answer is : P−3,Q−4,R−2,S−1

Graduate Pharmacy Aptitude Test (GPAT) 2006 Solved Paper

Question : 56 of 85

Marks: +1, -0

N-substitution of 4-phenylpiperidine4-ethyl-carboxylate derivatives results in nalgesics with varying activities. Match the substitutions with activities

GROUP I Substitution at N	GROUP II Analgesics
(P) −CH3	(1) Fentanyl
(Q) −CH2−CH2−(C6H4)−NH2	(2) Diphenoxylate
(R) −CH2−CH2−C−(C6H5)2−CN	(3) Pethidine
(S) −CH2−CH2−C6H5	(4) Anileridine

P-3, Q-1,R-4, S-2
P-4, Q-2,R-3, S-1
P-1, Q-2,R-3, S-4
P−3,Q−4,R−2,S−1

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