SSC CGL 10 Jun 2019 Shift 1 Paper

Sacred: connected with God or a god or dedicated to a religious purpose and so deserving veneration.
Perpetual: never ending or changing.
Pious: devoutly religious.
Profane: (of a person or their behavior) not respectful of religious practice; irreverent.
Profound: (of a person or statement) having or showing great knowledge or insight.
So, profane is the correct antonym.